Discngine Labs Live - Basel, Switzerland
Navigating developability challenges across advanced modalities: Computational tools & approaches
3:00 pm - 7:00 pm (CET)
Hyperion Hotel, Basel, Switzerland (and Virtual)
Join us in Basel, Switzerland, for another Discngine Labs event Live!
Explore how computational tools are helping scientists tackle the developability challenges of next-generation antibody therapeutics and connect with peers from industry and academia.
Since 2022, Discngine Labs' event series has brought together researchers and IT experts to share insights and discuss various topics in early drug discovery.
This edition will be held in-person and streamed live!
About the event
The biopharmaceutical landscape is evolving rapidly, with increasingly complex antibody modalities such as multispecifics and antibody–drug conjugates (ADCs) pushing the boundaries of therapeutic design.
While these innovative formats offer new treatment possibilities, they also introduce greater developability challenges compared to conventional monoclonal antibodies, including increased aggregation risks and higher viscosity, poor solubility, and reduced stability.
So, how are in-silico developability practices adapting to these complex antibody formats?
At this scientific gathering, you will discover innovative in-silico approaches and practical workflows that support predictive assessment of key physicochemical properties for advanced modalities early in the discovery process; ultimately guiding a rational construct design and reducing downstream risks related to formulation and manufacturability.
What to expect?
Scientific talks from pharma researchers sharing their latest discoveries and in-silico workflows for mitigating developability risks in complex antibody modalities
An expert panel providing insights and best practices for early developability assessment, featuring both early and late-stage experts.
Networking opportunities with industry peers and casual discussions over food and drinks
Meet the speakers
Bruck Taddese, PhD
Senior Expert II Data Science, at Novartis Biologics Research Center
Giuseppe Licari, PhD
Principal Scientist at Merck KGaA
Tarik Khan, PhD
CMC Expert at Roche
Peter Schmidtke, PhD
Product Owner, 3dpredict/Ab at Discngine
More speakers to be announced soon…
Agenda
| Time (CET) | Session |
|---|---|
| 3:00 – 3:30 pm | Welcome Reception |
| 3:30 – 4:00 pm | Plenary talk: Bruck Taddese, PhD Embedding in Silico Workflows in Biologics Drug Discovery |
| 4:00 – 4:30 pm | Presentation: Peter Schmidtke, PhD 3dpredict/Ab: Scalable High Quality Developability Predictions |
| 4:30 – 4:45 pm | Break |
| 4:45 – 5:15 pm | Presentation: Giuseppe Licari, PhD Presentation Title to be Announced |
| 5:15 – 5:45 pm | Roundtable: Tarik Khan, PhD (chair), Bruck Taddese, PhD, Giuseppe Licari, PhD Integrating Late-Stage Insights into Early Design of Next-Generation Antibodies |
| From 5:45 pm | Networking Reception |
Location
We look forward to welcoming you at the Hyperion Hotel in Basel, Switzerland.
Hyperion Hotel Basel
