Discngine Labs Live - Basel, Switzerland
Navigating Developability Challenges Across Antibody Modalities: Computational Tools & Approaches
3:00 pm - 7:00 pm (CET)
Hyperion Hotel, Basel, Switzerland (and Virtual)
Free event
Join us in Basel, Switzerland, for another Discngine Labs event Live!
Explore how computational tools are helping scientists tackle developability challenges in the development of both conventional and advanced antibody therapeutics, and connect with industry peers.
Since 2022, Discngine Labs' event series has brought together researchers and IT experts to share real-world experience and exchange ideas on various topics in early drug discovery.
This edition will be held in-person and streamed live!
About the event
The biopharmaceutical landscape is evolving rapidly, with increasingly complex antibody modalities such as multispecifics and antibody–drug conjugates (ADCs) pushing the boundaries of therapeutic design.
While these innovative formats offer new treatment possibilities, they also introduce greater developability challenges, including increased aggregation risks and higher viscosity, poor solubility, and reduced stability.
So, how are in-silico developability practices adapting to support both traditional monoclonal antibodies (mAbs) and next-generation antibody formats?
At this scientific gathering, you will discover innovative in silico approaches and practical workflows that support predictive assessment of key physicochemical properties across mAbs and advanced modalities early in the discovery process; ultimately guiding a rational construct design and reducing downstream risks related to formulation and manufacturability.
What to expect?
Scientific talks from pharma researchers sharing their latest discoveries and in-silico workflows for mitigating developability risks
An expert panel providing insights and best practices for early developability assessment, featuring both early and late-stage experts
Networking opportunities with industry peers and casual discussions over food and drinks
Meet the speakers
Bruck Taddese, PhD
Senior Expert II, Data Science, at Novartis Biologics Research Center
Giuseppe Licari, PhD
Principal Scientist at Merck KGaA
Tarik Khan, PhD
CMC Expert at Roche
Peter Schmidtke, PhD
Product Owner, 3dpredict/Ab at Discngine
Andrew Henry, PhD
Principal scientist at Chemical Computing Group
Agenda
| Time (CET) | Session |
|---|---|
| 3:00 – 3:30 pm | Welcome Reception |
| 3:30 – 4:00 pm | Plenary talk: Bruck Taddese, PhD Embedding in Silico Workflows in Biologics Drug Discovery |
| 4:00 – 4:30 pm | Presentation: Peter Schmidtke, PhD 3dpredict/Ab: Scalable High Quality Developability Predictions |
| 4:30 – 4:45 pm | Break |
| 4:45 – 5:15 pm | Presentation: Giuseppe Licari, PhD Optimizing Colloidal Stability and Viscosity of Multispecific Antibodies at the Drug Discovery-Development Interface |
| 5:15 – 5:45 pm | Roundtable: Tarik Khan, PhD (chair), Bruck Taddese, PhD, Andrew Henry, PhD and Giuseppe Licari, PhD Integrating Late-Stage Developability Insights into Early In Silico Antibody Design |
| From 5:45 pm | Networking Reception |
Location
We look forward to welcoming you at the Hyperion Hotel in Basel, Switzerland.
Hyperion Hotel Basel
