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Enhancing Life Science Research

NEWS FEED

Discover the latest from our organization

[Event] Discngine will be at the Bio-IT World Conference 2024

Next April, the Discngine Team will be in Boston for a unique event! Discngine is delighted to announce its participation in the Bio-IT World Conference & Expo, a unique event celebrating over two decades of groundbreaking advancements in precision medicine. Taking place from April 15 to 17, 2024, this event promises to be a pivotal moment in the convergence of life sciences, pharmaceuticals, clinical practice, healthcare, informatics, and technology.

Visit us >>

(May 2024)


[Material] A new brochure is available for Assay Catalog, a standardized assay inventory

The Discngine Assay Catalog provides rich biological context for experimental results, enforcing consistent annotations by following corporate standards. It gives drug discovery project teams a single source of truth across different assays and labs.

Download the Brochure >>

(February 2024)


[Success Story] How Discngine Assay enhanced overall screening activities at Bayer CropScience

Discover how Discngine has transformed Bayer CropScience's data management system with Discngine Assay resulting in a significant boost in Bayer's scientific research capabilities, enabling more time for innovation and less for manual data troubleshooting.

Blog post >>>

(January 2024)


[Discngine Labs] The Future of Bioassay Data - A FAIR Implementation Discussion?

Gain insights and hear the panel experiences on various aspects of FAIR implementation, including the current state of the FAIR-ness of assay data, success factors in the change process, applying FAIR principles to historical data, and assessing the FAIRness of public data sources.

Watch recording >>>

(November 2023)


[Success Story] Empowering digital transformation at L’Oréal with Discngine Assay Cloud solution

Digital technologies are reshaping the landscape of discovery and innovation. L’Oréal has been leading the charge in embracing digital transformation and data-driven processes. Collaborating with Discngine, they've successfully migrated multiple of their scientific software applications to the cloud, enhancing research and innovation!

Blog post >>>

(November 2023)


[Blog] How Discngine enhanced building blocks data handling for Medicinal Chemists – Pharma success story

See how Discngine contributed to the success of over 100 Medicinal Chemists from one of the Top 5 Pharma by building and implementing custom solution for Building Blocks data management.

Blog post >>>

(October 2023)


[Blog] How to best exploit 3D protein structures for ideation in SBDD?

Explore the insights from industry experts on how to manage vast 3D protein structures to facilitate new design ideas in SBDD

Blog post >>>

(September 2023)


[Video] How to exploit protein-ligand interactions for new design ideas? - Drug repurposing Use Case

See how to utilize 3decision Interaction Search to explore an entire PDB databank to identify existing drugs with similar protein-ligand interaction patterns to get new drug design ideas.

Watch video >>>

(September 2023)


[Blog] From legacy system to Discngine Assay: 5 steps to enhance assay data management

Find out how to recognize the need to migrate to an innovative assay data management system and Discngine can help.

Read more >>>

(August 2023)


[Discngine Meetup] Preliminary agenda is now live!

See what to expect at the Discngine Meetup 2023! The preliminary agenda with speakers, panelists, and partners is now live!

Check it out and join us >>>

(August 2023)


[Products] New release of Discngine Assay

We have updated our assay screening data management platform Discngine Assay to version 6.2. Discover the latest enhancements and get a sneak peek into what's coming next!

Read more >>>

(July 2023)


[Products] CLK selectivity study with 3decision

We have been exploring the structural basis of the CLK kinase inhibitors selectivity using the core features of 3decision. These insights can aid the development of more selective therapeutics. Watch our videos:

Efficient navigation and data sets generation: https://youtu.be/ENYfgyAVbwM

Quickly extract structural knowledge for design ideas: https://youtu.be/S1Fr2FqO55g

(June 2023)


[Events] Discngine at CCG NORTH AMERICAN UGM & Conference 2023

Join us at this event as Lorena Zara, Scientific Project Manager at Discngine, delivers an insightful talk titled "Binding Site Comparison - Current Pitfalls & Potential Solutions" on Friday 23rd.

Read more >>>

(June 2023)


[Blog] Five essential criteria for a healthy assay data management system

Co-written with our senior software architect, Plamen Petrov, this blog post highlights five essential criteria you need to efficiently manage your assay data.

Read more >>>

(May 2023)


[Events] Discngine at BioIT World Conference & Expo 2023

This year again, Discngine is exhibiting at the BioIT World conference in Boston. Our scientific and IT crew Eric Le RouxThomas BlarreLorena Zara and Riccardo Martini are getting ready to show you the latest developments of Discngine solutions and Mixed Reality technology for Drug Discovery. Visit booth #622!

Read more >>>

(May 2023)


[Events] Discngine at CCG EUROPEAN UGM & Conference 2023

Attending European CCG UGM? Peter Schmidtke, our Scientific Project Manager, will present "Binding Site Comparison - Current Pitfalls & Potential Solutions" at CCG’s European UGM & Conference in Munich, May 30-June 2.

More info and registration >>>

(May 2023)


[Products] Discover 3decision® by Discngine

In this new video, you will discover the efficient way of 3D protein structure data management through the general overview of Discngine’s software 3decision®. It is a protein structure repository and analytics software that allows you to streamline 3D structural data management and perform structural analysis.

Watch video >>>

(May 2023)


[Discngine Meetup] Event announcement and plenary

We are excited to announce that our third Discngine Meetup event is coming up this year on October 12th! The topic of the event is "New Drug Modalities: Evolving Needs in Scientific Informatics.” Our plenary speaker is Leonardo De Maria, Ph.D. from AstraZeneca. Join us!

More info and registration >>>

(April 2023)


[Products] The launch of Discngine assay

We have enhanced the functionalities of our Discngine assay software and transformed it into a cloud-first solution to help scientists working on screening campaigns streamline their lab workflows and easily manage plate-based assay data.

Discngine assay product page >>>

Free brochure >>>

(March 2023)


[Security] Discngine is ISO27001 certified

Discngine obtained ISO/IEC 27001:2013 certification for Information Security Management, which demonstrates its ability to protect customer’s sensitive data and information from unauthorized access and other cyber threats.

Free whitepaper >>>

(February 2023)


[Discngine Labs] What’s next after AlphaFold?

How are experts from both pharma and academia using AlphaFold and other ML-based technologies to develop methods that predict protein structures even more suitable for drug discovery applications? In our Discngine labs event, they showcased their work and engaged in an insightful discussion.

Watch recording >>>

(January 2023)

 

NEWSLETTER

 

Every quarter, receive unique content and specific information about Discngine and our industry

 

2024


2023


2022

 

PRESS

 
 

Press Releases

Feb 1, 2023 - Discngine obtains the ISO/IEC 27001 certification for Information Security management! Read

Jan 13, 2022 - Discngine partners up with ChemAxon to enhance its 3decision® platform for innovative Structure-Driven Drug Discovery! Read

May 12, 2020 - Discngine and LabVoice Announce Strategic Partnership. Read

Apr 6, 2020 - Discngine announces that Sosei Heptares will use its 3decision® software to create an unprecedented structural GPCR chemogenomics platform. Read

Sep 4, 2019 - Lundbeck selects Discngine’s 3decision® platform to leverage complex protein-ligand 3D structure data in the discovery of new treatments for brain diseases. Read

Apr 24, 2019 - Discngine and AbbVie, winners of the Innovative Practices Award at Bio-IT 2019! Read

Dec 11, 2017 - Discngine raises €1.1 million ($1.3M) in Series A funding round. Read

In the News

Feb 18, 2020 - 3decision® mentioned by mind Health [FR] : Quelles technologies pour aider à la mise au point des candidats médicaments? Read

Apr 18, 2019 - Winner of Bio-IT World’s Innovative Practices Award! Read

May 15, 2018 - Discngine receives €600,000 funding from Bpifrance. Read

Dec 14, 2018 - Funds raised by Discngine for advancement of its SaaS solution. Read

Oct 25, 2017 - LaBiotech.eu article about 3decision® Read

 
 

Scientific publications

Cheminformatics


High content/throughput screening

  • Chabord et al. '"High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes.", Stem Cells, 2013

  • Casagrande et al. "Effects of structurally related flavonoids on cell cycle progression of human melanoma cells: regulation of cyclin-dependent kinases CDK2 and CDK1.", Biochemical Pharmacology, 2001

Structure-Based Drug Design

3decision mentioned: